rr2011 just asked what I was thinking to ask but was faster ;-)rr2011 wrote:Have you verified that your Saffire MixControl software is correctly routing the audio where you need it?
I also use a Focusrite Scarlett 18i8, and know that if your MixControl audio routings are setup incorrectly you can definitely experience similar issues to what you are having now. You need to get the MixControl routings setup correctly before you'll have much luck working within your DAW.
The MixControl can be tricky sometimes...and the card not always works stand-alone without the Mixcontrol running, so it is worth to check, as I think the problem is there, now that you ruled out almost everything else